Conference Day One

Wednesday 13th September 2023

8:20 am Chairperson’s Opening Remarks

Unlocking the Secrets of the Skin Microbiome Through Sophisticated Research Tools, Sequencing & Data Analytics

8:30 am Powering Skin Microbiome Research Through Academia-Industry Partnerships

  • Se Jin Song Director of Research, UC San Diego Health Sciences

Synopsis

  • Revealing some of the industry-academic partnerships at UC San Diego
  • Exploring how such projects have progressed product development for products targeting the skin microbiome
  • Outlining future outlooks

9:00 am Exploring Gas Chromatography Mass Spectrometry Analysis for Skin Microbiome Research

Synopsis

  • Outlining volatilome, one of the most non-invasive samples that can be collected and could be used for disease monitoring, treatment efficacy, or even simply effects of lifestyle choices on personal smell. There remains a number of technical bottlenecks.
  • Demonstrating the low-cost, high throughput methodologies for volatilome analysis that use gas chromatography-mass spectrometry (GC-MS)
  • Exploring advanced molecular annotation for GC-MS data that extends recently introduced molecular networking methodology

9:30 am GxP Sequencing Services & The Future of Microbiome Analysis

Synopsis

  • Outlining pre-clinical study support & host-specific bioinformatics
  • Thinking beyond phase 1- GCP clinical trial support
  • Supporting CMC activities in LBP development
  • Exploring the future of microbiome analysis

9:40 am Utilizing Microbiome Engineering Tools to Treat Skin Diseases

Synopsis

  • Outlining how genetic and microbial engineering are key to enhancing microbial function on the skin
  • Using such tool to enhance safety, efficacy, or functionality in designing live biotherapeutic products
  • Outlining these tools in the context of skin diseases.

10:10 am
Speed Networking & Morning Break

Increasing Our Understanding of the Skin Microbiome to Enable Streamlined Product Development

11:30 am Redefining Our Understanding of What Makes a Healthy Skin Microbiome: Interindividual Differences & Healthy Aging

Synopsis

  • Uncovering the latest mechanistic understanding of healthy skin microbiome interactions
  • Understanding what contributes to a healthy microbiome
  • Exploring what encompasses ‘healthy aging’  

12:00 pm SkinDuo™: An Effective Preservative Free Topical Serum & Food Supplement Combo, with Lactiplantibacillus plantarum for Acne Mitigation

Synopsis

  • Exploring how skin microbiome tailoring is a challenging but crucial aspect of research in immune-mediated inflammatory skin diseases like acne
  • Revealing how common preservatives used in functional ingredients can impact the skin microbiota, leading to a decrease in commensal bacteria survival
  • SkinDuoTM, a topical serum formulated with Lactiplantibacillus plantarum and natural enhancers, shows promising results in mitigating acne by improving lipid production and reducing anti-inflammatory markers in human ex vivo sebaceous gland models and also on human subjects

12:10 pm Bridging Industry & Consumer Needs: The Gut-Skin Axis

  • Raja Sivamani Director of Research, Integrative Skin Science & Research

Synopsis

  • Exploring consumer needs, concerns and expectations when considering gut testing
  • Uncovering how industry can approach consumer needs in a practical way
  • Bridging the gap between gut and skin health concerns and solutions

12:40 pm
Lunch Break & Networking

Uncovering the Latest Advancements Across Cosmetic & Therapeutic Interventions for Skin Conditions

1:45 pm Using a Watercress Extract to Inhibit Bacterial Urease, Scavenge Ammonia & Soothe Skin as a Novel Treatment & Prevention in Incontinence Associated Dermatitis

Synopsis

  • Presentation of urease inhibiting data in-vitro on Proteus models
  • Demonstration of skin rejuvenating activity in a Labskin skin model. Antiinflammatory activity in a clinical trial of SLS-induced inflammation
  • Processing of watercress to yield a suitable extract for topical use

2:25 pm Translating Ancestral Skin Microbiome Research into Synergistic Skincare Products

  • Julia Durack Vice President of Research and Product Development, Symbiome

Synopsis

  • Exploring the ways our modern lifestyle influences the skin’s microbiome
  • Uncovering an evolutionary biology perspective of the skin microbiome
  • Translating ancestral microbiome research into skincare products  

2:45 pm Exploring Clinical Updates Across Acne Vulgaris Therapeutic Development

  • Hyun Kim Vice President - Clinical Development & Head of Clinical Operations, AOBiome

Synopsis

  • Highlighting current treatment options and challenges in acne vulgaris
  • Exploring the role of ammonia oxidizing bacteria in inflammation
  • Investigational B244 delivered as a topical spray for efficacy and safety in mild to moderate acne vulgaris

3:15 pm
Afternoon Coffee Break and Networking

Exploring Novel Research & Product Development Considerations to Produce Higher Quality Microbiome-Based Products

3:45 pm Your Products & the Microbiome: Ingredients Matter

  • Nicole Scott Chief Executive Officer & Founder, Cybele Microbiome

Synopsis

  • Harnessing the optimal synergy of ingredients for microbiome targeting skincare
  • Maximizing the product lifespan through sophisticated ingredient choices
  • Outlining different ingredient options available 

4:15 pm Roundtables:

Synopsis

  • Skin microbiome through women’s stages: pregnancy and menopause
  • Microbial biomarkers to predict and prevent skin conditions- screening infants
  • Uncovering the scalp microbiome
  • Therapeutic regulatory challenges  

5:00 pm Chairperson’s Closing Remarks

5:10 pm
End of Conference Day One