Conference Day One
Wednesday 13th September 2023
8:20 am Chairperson’s Opening Remarks
Unlocking the Secrets of the Skin Microbiome Through Sophisticated Research Tools, Sequencing & Data Analytics
8:30 am Powering Skin Microbiome Research Through Academia-Industry Partnerships
Synopsis
- Revealing some of the industry-academic partnerships at UC San Diego
- Exploring how such projects have progressed product development for products targeting the skin microbiome
- Outlining future outlooks
9:00 am Exploring Gas Chromatography Mass Spectrometry Analysis for Skin Microbiome Research
Synopsis
- Outlining volatilome, one of the most non-invasive samples that can be collected and could be used for disease monitoring, treatment efficacy, or even simply effects of lifestyle choices on personal smell. There remains a number of technical bottlenecks.
- Demonstrating the low-cost, high throughput methodologies for volatilome analysis that use gas chromatography-mass spectrometry (GC-MS)
- Exploring advanced molecular annotation for GC-MS data that extends recently introduced molecular networking methodology
9:30 am GxP Sequencing Services & The Future of Microbiome Analysis
Synopsis
- Outlining pre-clinical study support & host-specific bioinformatics
- Thinking beyond phase 1- GCP clinical trial support
- Supporting CMC activities in LBP development
- Exploring the future of microbiome analysis
9:40 am Utilizing Microbiome Engineering Tools to Treat Skin Diseases
Synopsis
- Outlining how genetic and microbial engineering are key to enhancing microbial function on the skin
- Using such tool to enhance safety, efficacy, or functionality in designing live biotherapeutic products
- Outlining these tools in the context of skin diseases.
10:10 am
Speed Networking & Morning Break
Increasing Our Understanding of the Skin Microbiome to Enable Streamlined Product Development
11:30 am Redefining Our Understanding of What Makes a Healthy Skin Microbiome: Interindividual Differences & Healthy Aging
Synopsis
- Uncovering the latest mechanistic understanding of healthy skin microbiome interactions
- Understanding what contributes to a healthy microbiome
- Exploring what encompasses ‘healthy aging’
12:00 pm SkinDuo™: An Effective Preservative Free Topical Serum & Food Supplement Combo, with Lactiplantibacillus plantarum for Acne Mitigation
Synopsis
- Exploring how skin microbiome tailoring is a challenging but crucial aspect of research in immune-mediated inflammatory skin diseases like acne
- Revealing how common preservatives used in functional ingredients can impact the skin microbiota, leading to a decrease in commensal bacteria survival
- SkinDuoTM, a topical serum formulated with Lactiplantibacillus plantarum and natural enhancers, shows promising results in mitigating acne by improving lipid production and reducing anti-inflammatory markers in human ex vivo sebaceous gland models and also on human subjects
12:10 pm Bridging Industry & Consumer Needs: The Gut-Skin Axis
Synopsis
- Exploring consumer needs, concerns and expectations when considering gut testing
- Uncovering how industry can approach consumer needs in a practical way
- Bridging the gap between gut and skin health concerns and solutions
12:40 pm
Lunch Break & Networking
Uncovering the Latest Advancements Across Cosmetic & Therapeutic Interventions for Skin Conditions
1:45 pm Using a Watercress Extract to Inhibit Bacterial Urease, Scavenge Ammonia & Soothe Skin as a Novel Treatment & Prevention in Incontinence Associated Dermatitis
Synopsis
- Presentation of urease inhibiting data in-vitro on Proteus models
- Demonstration of skin rejuvenating activity in a Labskin skin model. Antiinflammatory activity in a clinical trial of SLS-induced inflammation
- Processing of watercress to yield a suitable extract for topical use
2:25 pm Translating Ancestral Skin Microbiome Research into Synergistic Skincare Products
Synopsis
- Exploring the ways our modern lifestyle influences the skin’s microbiome
- Uncovering an evolutionary biology perspective of the skin microbiome
- Translating ancestral microbiome research into skincare products
2:45 pm Exploring Clinical Updates Across Acne Vulgaris Therapeutic Development
Synopsis
- Highlighting current treatment options and challenges in acne vulgaris
- Exploring the role of ammonia oxidizing bacteria in inflammation
- Investigational B244 delivered as a topical spray for efficacy and safety in mild to moderate acne vulgaris
3:15 pm
Afternoon Coffee Break and Networking
Exploring Novel Research & Product Development Considerations to Produce Higher Quality Microbiome-Based Products
3:45 pm Your Products & the Microbiome: Ingredients Matter
Synopsis
- Harnessing the optimal synergy of ingredients for microbiome targeting skincare
- Maximizing the product lifespan through sophisticated ingredient choices
- Outlining different ingredient options available
4:15 pm Roundtables:
Synopsis
- Skin microbiome through women’s stages: pregnancy and menopause
- Microbial biomarkers to predict and prevent skin conditions- screening infants
- Uncovering the scalp microbiome
- Therapeutic regulatory challenges